1. Get the right running shoes.
Wearing the right running shoes is the key to comfort and injury prevention. Visit a running specialty store to get fitted for the right running shoes for your foot type and running style. Also, make sure you don't run in worn-out running shoes – they should be replaced every 300-400 miles.
2. Learn the proper upper body form.Improper upper body form can lead to pain in your arms, shoulders, neck, and back. Try to keep your hands at waist level, right about where they might lightly brush your hip. Your arms should be at a 90 degree angle, with your elbows at your sides. Keep your posture straight and erect. Your head should be up, your back straight, and shoulders level.
More: Tips for Proper Running Form
Video - Proper Running Form
3. Try a run/walk approach.Most beginner runners start out using a run/walk technique because they don't have the endurance or fitness to run for extended periods of time. The run/walk method involves running for a short segment and then taking a walk break. As you continue with a run/walk program, the goal is to extend the amount of time you're running and reduce your walking time.