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Subtype classification and single and meta gene proliferation scores were predicted on an independent test set of 814 samples from the GEICAM 9906 clinical trial, a randomized Phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by paclitaxel 22 ivermectin for rosacea The study design assumed a dropout rate of 15 for the primary end point assessment time of 12 weeks after registration